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Glutathione in Brain Ageing and Neurodegenerative Disorders Gianni Benzi and Antonio Moretti 12
On the other hand, beneficial metabolites such as butyrate can activate cellular mechanisms for protein clearance: butyrate readily crosses the BBB and can inhibit histone deacetylases, thereby activating gene expression programs that enhance autophagy and reduce toxic protein aggregates [55]
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doi: 10.1038/nm.1959 70 NarlaSAzzamMTownsendSVellaichamyGMarzanoAVAlaviAet al
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